Potential Health Effects of Taking Creatine

Creatine is a naturally occurring substance present in minute levels in some foods such as seafood and meat, as well as in the human body. It is essential for energy metabolism, especially in high-intensity, short-duration exercises such as weightlifting and sprinting. Creatine has gained appeal as a dietary supplement due to its possible benefits in improving sports performance. However, as with any dietary supplement, there are some potential health risks linked with its use. In this response, we will go over the specific negative side effects of taking creatine, addressing a variety of potential issues.


Scroll to know the negative effects of taking creatine

Kidney Trouble:

One of the most serious effects of creatine supplementation is its potential impact on renal function. Creatine is broken down into creatinine levels, a waste product produced by the kidneys. A few research studies have found that people who take creatine supplements have higher creatinine levels. While this rise is normally within the typical range, people who have pre-existing kidney diseases or have reduced renal function may have an additional load on their kidneys.


Creatine has a water-retaining function in the body, which causes a rise in the water content of muscle cells. As a consequence, creatine users may suffer increased water weight and, as a result, an increased likelihood of dehydration if they do not take enough fluids. Dehydration can cause a variety of problems, including muscle cramps, disorientation, and decreased physical performance.

Irritable Bowel Syndrome:

When taking creatine supplements, some people may have gastrointestinal difficulties such as bloating, diarrhea, and stomach discomfort. This could be related to creatine osmotic effects, which suck water into the intestines, resulting in higher fluid content and gastrointestinal problems.

Gaining Weight:

Creatine supplementation may result in an initial weight gain, owing to greater water retention inside muscle cells. While this may be advantageous for athletes looking to increase muscle development and strength, it may be detrimental to persons attempting to maintain or lower their body weight. The extra water weight might obscure genuine fat reduction and offer the impression of improvement.

Possibly Liver Strain:

Although there is some indication that creatine supplementation may be harmful to liver health, additional study is needed to establish a definitive correlation. Individuals with pre-existing liver issues, on the other hand, should take caution and see a physician before using creatine.

Medications Interactions:

Creatine could interact with certain medications, notably those that can impair renal function, such as NSAIDs and diuretics. These interactions may aggravate the unfavorable effects on the kidneys or change the medication’s efficacy.

Long-Term Consequences:

While short-term studies have shown that creatine supplementation is safe when used as advised, the long-term implications of extended and high-dose creatine consumption are unknown. More research is needed to completely comprehend the possible effects of long-term creatine supplementation on numerous aspects of health.


It is important to note that the vast majority of people who take creatine do not experience any serious side effects. However, before beginning any dietary supplement, contact a healthcare expert, particularly if you have pre-existing medical conditions or take drugs that may interact with creatine.

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